The dysregulation of the hypothalamic–pituitary–adrenal axis in diet-induced prediabetic male Sprague Dawley rats

Abstract Background Altered function of the hypothalamic–pituitary–adrenal (HPA) axis in type 2 diabetic patients, a condition preceded by pre-diabetes, has been shown to increase the risk of depression as well as cause downstream effects resulting in upregulation of gluconeogenesis and dyslipidemia...

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Hlavní autoři:	Palesa Mosili, Bongeka Cassandra Mkhize, Phikelelani Ngubane, Ntethelelo Sibiya, Andile Khathi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-12-01
Edice:	Nutrition & Metabolism
Témata:	Prediabetes High-fat high-carbohydrate diet Hypothalamic–pituitary–adrenal axis Cortisol Corticosterone Stress
On-line přístup:	https://doi.org/10.1186/s12986-020-00532-1
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