Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7

Abstract The emergence of drug-resistant bacteria has become a major problem worldwide. Bacterial dipeptidyl peptidases 7 and 11 (DPP7s and DPP11s), belonging to the family-S46 peptidases, are important enzymes for bacterial growth and are not present in mammals. Therefore, specific inhibitors for t...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Akihiro Nakamura, Yoshiyuki Suzuki, Yasumitsu Sakamoto, Saori Roppongi, Chisato Kushibiki, Natsuri Yonezawa, Masato Takahashi, Yosuke Shida, Hiroaki Gouda, Takamasa Nonaka, Nobutada Tanaka, Wataru Ogasawara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2021-04-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-021-86965-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!