SIRPA, BTN3A1, and TDO2 in osteosarcoma: a prognostic triad with therapeutic implications from integrated genomic and pharmacogenomic data

Abstract The limited understanding of the prognostic implications of immune checkpoint molecules in osteosarcoma (OS) poses significant challenges for improving patient outcomes. There is a gap in the identification of reliable biomarkers that can predict treatment response and prognosis in OS patie...

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Detalhes bibliográficos

Principais autores:	Han-jing Zhang, Zhi-Jun Yang, Wen Huang, Dan Chen, Jie Xiang, Wen-kang Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-08-01
Colecção:	Journal of Orthopaedic Surgery and Research
Assuntos:	Osteosarcoma Immune checkpoints Prognosis Immune therapy SIRPA
Acesso em linha:	https://doi.org/10.1186/s13018-025-06171-7
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