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Acute malaria dysregulates specialized lymph node macrophages to suppress vaccine-elicited protection against the Ebola virus

ABSTRACT The filovirus, Ebola virus (EBOV), causes outbreaks of EBOV disease (EVD) throughout equatorial Africa. ERVEBO is a replication-competent recombinant vesicular stomatitis virus-vectored vaccine encoding the EBOV glycoprotein (recombinant vesicular stomatitis virus [rVSV]/EBOV), which is lic...

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Wedi'i Gadw mewn:
Prif Awduron: Jonah Elliff, Lindsey Grady, Kyle L. O'Donnell, Caitlin Messingham, Kai J. Rogers, Jobaida Akther, Andrew Thurman, Rahul Vijay, Alejandro Pezzulo, Troy Randall, Andrea Marzi, Noah S. Butler, Wendy Maury
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2026-02-01
Cyfres:mBio
Pynciau:
vaccine
filovirus
Ebola virus
Plasmodium
lymph node
interferon gamma
Mynediad Ar-lein:https://journals.asm.org/doi/10.1128/mbio.02796-25
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