TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells

Abstract Background Pulmonary hypertension (PH) is a life-threatening cardio-pulmonary disorder. Whether natural killer (NK) cells could act as participants in PH and the mechanism by which NK cells moderate pulmonary vascular remodeling has not been fully elucidated. Methods Single-cell RNA sequenc...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Li-Wei Wu, Min Chen, Dai-Ji Jiang, Chen-Yu Jiang, Yi-Wei Liu, Bei Feng, Chen-Fei Shi, Xu Huang, Xu Zhang, Xiao-He Xu, Xing-Liang Zhou, Yi Shen, Tian-Yu Liu, Lin-Cai Ye, Yang-Yang He, Hao Zhang, Yi Yan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-05-01
Colecção:	Respiratory Research
Assuntos:	Pulmonary hypertension Single cell RNA-seq Natural killer cells TCF7 Pulmonary arterial smooth muscle cells
Acesso em linha:	https://doi.org/10.1186/s12931-025-03276-9
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!