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Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo

Abstract Background Toxoplasma gondii is an obligate protozoan parasite capable of infecting a wide range of warm-blooded animals and humans. Current treatment options, primarily pyrimethamine and sulfadiazine, have limitations, such as high recurrence rates, long treatment durations, and limited ef...

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Principais autores: Lu Wang, Bintao Zhai, Chen Wang, Hany M. Elsheikha, Haiting Guo, Xiao-Nan Zheng, Chun‑Xue Zhou, Xing-Quan Zhu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-12-01
Serier:Parasites & Vectors
Fag:
Toxoplasma gondii
Glabridin
Metabolomics
Transcriptomics
Survival rate
Online adgang:https://doi.org/10.1186/s13071-024-06610-0
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