Identification of tumor-specific T cell signature predicting cancer immunotherapy response in bladder cancer by multi-omics analysis and experimental verification

Abstract Background Numerous gene signatures predicting the prognosis of bladder cancer have been identified. However, a tumor-specific T cell signature related to immunotherapy response in bladder cancer remains under investigation. Methods Single-cell RNA and TCR sequencing from the Gene expressio...

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Hauptverfasser:	Xiufeng Liu, Chujun Chen, Jiashan Li, Linna Li, Meng Ma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-07-01
Schriftenreihe:	Cancer Cell International
Schlagworte:	Bladder cancer Tumor-specific T cells Prognostic signature Immunotherapy Multi-omics analysis
Online-Zugang:	https://doi.org/10.1186/s12935-024-03447-6
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