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BHLHE40 Maintains the Stemness of PαS Cells In Vitro by Targeting <i>Zbp1</i> through the Wnt/β-Catenin Signaling Pathway

Primary bone mesenchymal stem cells (BMSCs) gradually lose stemness during in vitro expansion, which significantly affects the cell therapeutic effects. Here, we chose murine PαS (SCA-1<sup>+</sup>PDGFRα<sup>+</sup>CD45<sup>−</sup>TER119<sup>−</sup>) cells as representative of BMSCs and aimed to exp...

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Principais autores: Menglong Hu, Yueming Tian, Xuenan Liu, Qian Guo, Dazhuang Lu, Xu Wang, Longwei Lv, Xiao Zhang, Yunsong Liu, Yongsheng Zhou, Ping Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-08-01
coleção:Biomedicines
Assuntos:
BHLHE40
culture in vitro
PαS cells
stemness
Wnt/β-catenin signaling pathway
<i>Zbp1</i>
Acesso em linha:https://www.mdpi.com/2227-9059/11/8/2190
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