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Solubility measurement of verapamil for the preparation of developed nanomedicines using supercritical fluid

Abstract A static method is employed to determine the solubilities of verapamil in supercritical carbon dioxide (SC-CO2) at temperatures between 308 and 338 K and pressures between 12 and 30 MPa. The solubility of verapamil in SC-CO2 expressed as mole fraction are in the range of 3.6 × 10–6 to 7.14 ...

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Bibliografische Detailangaben
Hauptverfasser: Nadia Esfandiari, Nedasadat Saadati Ardestani, Ratna Surya Alwi, Adrián Rojas, Chandrasekhar Garlapati, Seyed Ali Sajadian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2023-10-01
Schriftenreihe:Scientific Reports
Online-Zugang:https://doi.org/10.1038/s41598-023-44280-7
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