MVA-based vaccine candidates expressing SARS-CoV-2 prefusion-stabilized spike proteins of the Wuhan, Beta or Omicron BA.1 variants protect transgenic K18-hACE2 mice against Omicron infection and elicit robust and broad specific humoral and cellular immune responses

Despite the decrease in mortality and morbidity due to SARS-CoV-2 infection, the incidence of infections due to Omicron subvariants of SARS-CoV-2 remains high. The mutations acquired by these subvariants, mainly concentrated in the receptor-binding domain (RBD), have caused a shift in infectivity an...

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मुख्य लेखकों:	Patricia Pérez, David Astorgano, Guillermo Albericio, Sara Flores, Cristina Sánchez-Corzo, María A. Noriega, Pedro J. Sánchez-Cordón, Nuria Labiod, Rafael Delgado, José M. Casasnovas, Mariano Esteban, Juan García-Arriaza
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2024-08-01
श्रृंखला:	Frontiers in Immunology
विषय:	COVID-19 SARS-CoV-2 MVA-based vaccine variants of concern S protein immunogenicity
ऑनलाइन पहुंच:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1420304/full
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