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Advancing crush syndrome management: the potent role of Sodium zirconium cyclosilicate in early hyperkalemia intervention and survival enhancement in a rat model

Background: Crush Syndrome (CS), a severe trauma resulting from prolonged muscle compression, is commonly seen in large-scale disasters such as earthquakes. It not only causes localized tissue damage but also triggers electrolyte imbalances, particularly hyperkalemia, increasing the risk of early mo...

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Main Authors: Duo Li, Yan Zhang, Yuansen Chen, Bofan Yang, Jianwen Chen, Jie Shi, Xiaoqin Guo, Yanqing Liu, Li Zhang, Qi Lv, Haojun Fan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Pharmacology
Subjects:
crush syndrome
Sodium zirconium cyclosilicate
hyperkalemia
rat model
survival rate
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1381954/full
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