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Post-treatment with the PPAR-γ agonist pioglitazone inhibits inflammation and bacterial growth during Klebsiella pneumonia

Abstract Agonists of peroxisome proliferator-activated receptor (PPAR)-γ have been suggested as potential adjuvant therapy in bacterial pneumonia because of their capacity to inhibit inflammation and enhance bacterial clearance. Previous studies only assessed the effects of pretreatment with these c...

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Autors principals: Ivan Ramirez-Moral, Bianca Lima Ferreira, Alex F. de Vos, Tom van der Poll
Format: Artigo
Idioma:Inglês
Publicat: BMC 2021-08-01
Col·lecció:Respiratory Research
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Accés en línia:https://doi.org/10.1186/s12931-021-01823-8
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