The development of a bioanalytical method for the simultaneous analysis of gentamicin and tacrolimus in Rat whole blood using UHPLC–MS/MS

Abstract Tacrolimus (TAC) is commonly administered to patients who have undergone organ transplantation to prevent the immune system from rejecting the transplanted organ. Multidrug-resistant bacterial infections are the most frequent complications during the first-month post-transplantation. Old an...

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Hauptverfasser:	Shrooq Altaweel, Ann Van Schepdael, Erwin Adams, Aliyah Almomen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-03-01
Schriftenreihe:	Scientific Reports
Schlagworte:	UHPLC–MS/MS Gentamicin Tacrolimus Rats whole blood Ion pairing reagent
Online-Zugang:	https://doi.org/10.1038/s41598-025-92418-6
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