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The genomics of oxidative DNA damage, repair, and resulting mutagenesis

Reactive oxygen species are a constant threat to DNA as they modify bases with the risk of disrupting genome function, inducing genome instability and mutation. Such risks are due to primary oxidative DNA damage and also mediated by the repair process. This leads to a delicate decision process for t...

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Autor principal: Anna R. Poetsch
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science (AAAS) 2020-01-01
Col·lecció:Computational and Structural Biotechnology Journal
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2001037019304209
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