Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs

Abstract Single cell spatial interrogation of the immune-structural interactions in COVID −19 lungs is challenging, mainly because of the marked cellular infiltrate and architecturally distorted microstructure. To address this, we develop a suite of mathematical tools to search for statistically sig...

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Bibliografiske detaljer

Principais autores:	Praveen Weeratunga, Laura Denney, Joshua A. Bull, Emmanouela Repapi, Martin Sergeant, Rachel Etherington, Chaitanya Vuppussetty, Gareth D. H. Turner, Colin Clelland, Jeongmin Woo, Amy Cross, Fadi Issa, Carlos Eduardo de Andrea, Ignacio Melero Bermejo, David Sims, Simon McGowan, Yasemin-Xiomara Zurke, David J. Ahern, Eddie C. Gamez, Justin Whalley, Duncan Richards, Paul Klenerman, Claudia Monaco, Irina A. Udalova, Tao Dong, Agne Antanaviciute, Graham Ogg, Julian C. Knight, Helen M. Byrne, Stephen Taylor, Ling-Pei Ho
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2023-11-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-023-42421-0
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