Drinking water disinfection byproduct iodoacetic acid affects thyroid hormone synthesis in Nthy-ori 3–1 cells

Iodoacetic acid (IAA) is an emerging and the most genotoxic iodinated disinfection byproduct to date. IAA can disrupt the thyroid endocrine function in vivo and in vitro, but the underlying mechanisms remain unclear. In this work, transcriptome sequencing was used to investigate the effect of IAA on...

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Bibliografiske detaljer

Principais autores:	Jingyi Xiao, Yujie Sha, Yuwen Huang, Kunling Long, Huan Wu, Yan Mo, Qiyuan Yang, Shengkun Dong, Qiang Zeng, Xiao Wei
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2023-06-01
Serier:	Ecotoxicology and Environmental Safety
Fag:	Drinking water Disinfection byproducts Iodoacetic acid Thyroid hormone Iodine uptake Oxidative stress
Online adgang:	http://www.sciencedirect.com/science/article/pii/S014765132300430X
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