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Inactivation of Heparin by Cationically Modified Chitosan

This study was performed to evaluate the ability of N-(2-hydroxypropyl)-3-tri methylammonium chitosan chloride (HTCC), the cationically modified chitosan, to form biologically inactive complexes with unfractionated heparin and thereby blocking its anticoagulant activity. Experiments were carried out...

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Furkejuvvon:
Váldodahkkit: Barbara Lorkowska-Zawicka, Kamil Kamiński, Justyna Ciejka, Krzysztof Szczubiałka, Magdalena Białas, Krzysztof Okoń, Dariusz Adamek, Maria Nowakowska, Jacek Jawień, Rafał Olszanecki, Ryszard Korbut
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2014-06-01
Ráidu:Marine Drugs
Fáttát:
chitosan
HTCC
unfractionated heparin
heparin antidote
protamine
coagulation
hepatotoxicity
Liŋkkat:http://www.mdpi.com/1660-3397/12/7/3953
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