Frontiers in Antibody–Drug Conjugates: Mechanisms, Design Innovations, and Clinical Applications in Targeted Cancer Therapy

Antibody–drug conjugates (ADCs) represent a transformative class of targeted therapies designed to deliver potent cytotoxic agents specifically to tumor cells, minimizing systemic toxicity. This review provides a comprehensive overview of ADCs, detailing their mechanisms of action, design strategies...

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Detalhes bibliográficos

Principais autores:	Xinghan Li, Jiaming Liu, Yitong Meng, Jun Li, Jieling Zhao, Dequan Liu, Xiaodong Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-02-01
coleção:	Pharmaceuticals
Assuntos:	antibody–drug conjugates cytotoxic agents mechanisms of action payload design clinical advancements
Acesso em linha:	https://www.mdpi.com/1424-8247/19/2/324
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