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Using acute tryptophan depletion to investigate predictors of treatment response in adolescents with major depressive disorder: study protocol for a randomised controlled trial

Abstract Background Selective serotonin reuptake inhibitors (SSRIs) are amongst the most prescribed antidepressants for adolescents with depressive symptoms and major depressive disorder. However, SSRIs have significant shortcomings as a first-line treatment considering that not all patients respond...

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Principais autores: Richard M. Stewart, Sean D. Hood, Pradeep Rao, Julia K. Moore, Kevin C. Runions, Susannah E. Murphy, Janice W. Y. Wong, Florian D. Zepf
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-08-01
Serier:Trials
Fag:
Depression
Children
Adolescents
Serotonin
Tryptophan depletion
Pharmacology
Online adgang:http://link.springer.com/article/10.1186/s13063-018-2791-4
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