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IL-6 trans-signaling in cystic fibrosis bronchial cells potentiates TNF-α-driven ICAM-1 expression

IntroductionPseudomonas aeruginosa is gram-negative bacillus that causes chronic airway infections, leading to severe pulmonary inflammation in cystic fibrosis. This bacterial infection is frequently associated with a massive recruitment of neutrophils and an abnormal increase in production of infla...

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Principais autores: John Lin, Lyvia Fourcade, Lucie Roussel, Matthew Marabella, Julie Bérubé, Dao Nguyen, Simon Rousseau
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-09-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
Pseudomonas aeruginosa
cystic fibrosis transmembrane regulator
cystic fibrosis
pulmonary exacerbations
inflammation
IL-6 trans-signaling
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2025.1566482/full
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