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Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets

Parasites from the genus Plasmodium are the causative agents of malaria. The mobility, infectivity, and ultimately pathogenesis of Plasmodium falciparum rely on a macromolecular complex, called the glideosome. At the core of the glideosome is an essential and divergent Myosin A motor (PfMyoA), a fir...

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Autors principals: Dihia Moussaoui, James P Robblee, Daniel Auguin, Elena B Krementsova, Silvia Haase, Thomas CA Blake, Jake Baum, Julien Robert-Paganin, Kathleen M Trybus, Anne Houdusse
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2020-10-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/60581
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