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Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital

Abstract Background Although the over-the-counter H1 receptor antagonist diphenhydramine is not a common drug of abuse, it was recently recognized as one of the substances causing acute poisoning in patients attempting suicide that led to admissions to our hospital emergency room. Case presentation...

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Principais autores: Koichiro Adachi, Satoru Beppu, Mariko Terashima, Wataru Kobari, Makiko Shimizu, Hiroshi Yamazaki
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-08-01
Serier:Journal of Pharmaceutical Health Care and Sciences
Fag:
Drug monitoring data
Liver damage
Pharmacokinetic prediction
Total bilirubin
Online adgang:https://doi.org/10.1186/s40780-021-00215-w
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