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Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters

<p>Abstract</p> <p>Background</p> <p>Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are no licensed preventative measures for hMPV infections. Using a variant of hMPV/NL/1/00 that does not req...

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Bibliografiske detaljer
Principais autores: Guzzetta Jeanne M, MacPhail Mia, Kaur Jasmine, Schickli Jeanne H, Spaete Richard R, Tang Roderick S
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2008-06-01
Serier:Virology Journal
Online adgang:http://www.virologyj.com/content/5/1/69
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