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Soluble Notch agonist enables human ameloblast maturation and enamel-like tissue formation for tooth regeneration

Abstract Enamel, the hardest mineralized material in the human body, protects the underlying living tissues, the dentin and pulp of the tooth. However, over 90% of adults have lost or damaged enamel and cannot regenerate the protective structure due to lack of enamel-producing cells, ameloblasts. iP...

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Váldodahkkit: Anjali P. Patni, Rubul Mout, Ammar Alghadeer, Rachel H. Moore, Samera Nademi, Brandon J. Ausk, Philippe Huber, Riya Keshri, Mary Regier, Robert A. Cornell, Ted Gross, Benjamin S. Freedman, George Q. Daley, David Baker, Julie Mathieu, Hannele Ruohola-Baker
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Publishing Group 2026-03-01
Ráidu:International Journal of Oral Science
Liŋkkat:https://doi.org/10.1038/s41368-026-00429-4
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