Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon

ABSTRACT Dengue virus (DENV) is the most widespread arbovirus, causing symptoms ranging from dengue fever to severe dengue, including hemorrhagic fever and shock syndrome. Four serotypes of DENV (DENV-1 to -4) can infect humans; however, no anti-DENV drug is available. To facilitate the study of ant...

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Κύριοι συγγραφείς:	Mingyue Hu, Wan-Fei Li, Tiantian Wu, Yang Yang, Guoquan Chen, Tongling Chen, Yongchen Liu, Yaqing Mei, De Wu, Youchuan Wei, Tingrong Luo, Hong-Jie Zhang, Yi-Ping Li
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology 2023-08-01
Σειρά:	Microbiology Spectrum
Θέματα:	DENV adaptive mutation antiviral compound arylnaphthalene lignans infectious clone replicon
Διαθέσιμο Online:	https://journals.asm.org/doi/10.1128/spectrum.00423-23
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