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Gene Coexpression Connectivity Predicts Gene Targets Underlying High Ionic-Liquid Tolerance in Yarrowia lipolytica

ABSTRACT Microbial tolerance to organic solvents such as ionic liquids (ILs) is a robust phenotype beneficial for novel biotransformation. While most microbes become inhibited in 1% to 5% (vol/vol) IL (e.g., 1-ethyl-3-methylimidazolium acetate), we engineered a robust Yarrowia lipolytica strain (YlC...

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Principais autores: Caleb Walker, Seunghyun Ryu, Sergio Garcia, David Dooley, Brian Mendoza, Cong T. Trinh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-08-01
coleção:mSystems
Assuntos:
Yarrowia lipolytica
oleaginous yeast
ionic liquid
solvent tolerance
robustness
dynamic RNA-Seq
Acesso em linha:https://journals.asm.org/doi/10.1128/msystems.00348-22
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