Cyclosporine Affects the Main Virulence Factors of <i>Cryptococcus neoformans</i> In Vitro

This study aimed to investigate the effects of cyclosporine on the morphology, cell wall structure, and secretion characteristics of <i>Cryptococcus neoformans</i>. The minimum inhibitory concentration (MIC) of cyclosporine was found to be 2 µM (2.4 µg/mL) for the H99 strain. Yeast cells treated wit...

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Autors principals:	Iara Bastos de Andrade, Dario Corrêa-Junior, Vinicius Alves, Maria Helena Galdino Figueiredo-Carvalho, Marcos Vinicius Santos, Marcos Abreu Almeida, Alessandro Fernandes Valdez, Leonardo Nimrichter, Rodrigo Almeida-Paes, Susana Frases
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-04-01
Col·lecció:	Journal of Fungi
Matèries:	cyclosporine <i>Cryptococcus neoformans</i> capsule calcineurin biology virulence
Accés en línia:	https://www.mdpi.com/2309-608X/9/4/487
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