Production and purification of methionine gamma-lyase from Iranian soil mulds: investigation of physicochemical properties and anticancer effects

Abstract Cancer’s rising global incidence necessitates innovative therapies targeting the unique metabolic vulnerabilities of tumor cells. This study investigates microbial methionine gamma-lyase (MGL), an enzyme that depletes methionine, as a potential anticancer agent. Elevated methionine levels d...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Matin Nasirian, Ali Arab-SadeghAbadi, Mohsen Mobini-Dehkordi, Sadegh Farhadian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-08-01
coleção:	BMC Cancer
Assuntos:	Muld native strains Methionine gamma-lyase Anti-cancer enzyme Gene expression BCL-2 Caspase-3
Acesso em linha:	https://doi.org/10.1186/s12885-025-14754-0
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!