Oligonucleotide Therapeutics: From Discovery and Development to Patentability

Following the first proof of concept of using small nucleic acids to modulate gene expression, a long period of maturation led, at the end of the last century, to the first marketing authorization of an oligonucleotide-based therapy. Since then, 12 more compounds have hit the market and many more ar...

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Autors principals:	Lara Moumné, Anne-Céline Marie, Nicolas Crouvezier
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-01-01
Col·lecció:	Pharmaceutics
Matèries:	oligonucleotides antisense small interfering RNA exon skipping small activating RNA microRNA
Accés en línia:	https://www.mdpi.com/1999-4923/14/2/260
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