ATLAS-seq: a microfluidic single-cell TCR screen for antigen-reactive TCRs
Abstract Discovering antigen-reactive T cell receptors (TCRs) is central to developing effective engineered T cell immunotherapies. However, the conventional technologies for isolating antigen-reactive TCRs (i.e., major histocompatibility complex (MHC) multimer staining) focus on high-affinity inter...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Portfolio
2025-01-01
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| Серии: | Nature Communications |
| Online-ссылка: | https://doi.org/10.1038/s41467-024-54675-3 |
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