Undifferentiated pleomorphic sarcoma as a rare extracolonic manifestation in Lynch syndrome with MLH1 germline mutation: a case report

Undifferentiated pleomorphic sarcoma (UPS) is a rare and highly aggressive soft tissue sarcoma that typically occurs in the extremities but is rarely found in the retroperitoneal cavity. Despite the documented cases of sarcomas in patients with Lynch syndrome (LS), the relationship between these mal...

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Главные авторы:	Yuxing Chen, Yilin Xiao, Ruihan Li, Mengjiao Wu, Yan Zong, Min Jin, Xiaona Chang, Hongli Liu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2026-04-01
Серии:	Frontiers in Oncology
Предметы:	Lynch syndrome mismatch repair deficiency MLH1 variant synchronous malignancies undifferentiated pleomorphic sarcoma
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1793258/full
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