Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway

Abstract Background We investigated the role of the ETS-1 transcription factor in Head and Neck Squamous Cell Carcinoma (HNSCC) in multiple cisplatin-resistant HNSCC cell lines. Methods We examined its molecular link with SRC and MEK/ERK pathways and determined the efficacy of either MEK/ERK inhibit...

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Principais autores:	Zejia Yang, Jipei Liao, Brandon A. Carter-Cooper, Rena G. Lapidus, Kevin J. Cullen, Hancai Dan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-05-01
coleção:	BMC Cancer
Assuntos:	Head and neck squamous cell carcinoma HNSCC ETS-1 Cisplatin resistance SRC MEK/ERK
Acesso em linha:	http://link.springer.com/article/10.1186/s12885-019-5664-7
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