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Assessment of progression of pulmonary fibrosis based on metabonomics and analysis of intestinal microbiota

The main purpose of this study was to explore the changes of biomarkers in different developmental stages of bleomycin-induced pulmonary fibrosis (PF) in rats via comprehensive pathophysiology, UPLC-QTOF/MS metabonomic technology, and 16S rRNA gene sequencing of intestinal microbiota. The rats were...

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Principais autores: Jia-qi Liu, Hong-bing Zhou, Wan-fu Bai, Jia Wang, Qian Li, Li-ya Fan, Hong Chang, Song-li Shi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:
Pulmonary fibrosis
disease progression
metabonomics
intestinal microbiota
biomarker
Acesso em linha:https://www.tandfonline.com/doi/10.1080/21691401.2024.2326616
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