Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids

Abstract Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na+/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses in 2012 enables target-based development of HBV/HDV...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Michael Kirstgen, Kira Alessandra Alicia Theresa Lowjaga, Simon Franz Müller, Nora Goldmann, Felix Lehmann, Sami Alakurtti, Jari Yli-Kauhaluoma, Dieter Glebe, Joachim Geyer
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2020-12-01
Serie:	Scientific Reports
Accesso online:	https://doi.org/10.1038/s41598-020-78618-2
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!