Anti-hyperalgesic and anti-inflammatory effects of 4R-tobacco cembranoid in a mouse model of inflammatory pain

Abstract 4R is a tobacco cembranoid that binds to and modulates cholinergic receptors and exhibits neuroprotective and anti-inflammatory activity. Given the established function of the cholinergic system in pain and inflammation, we propose that 4R is also analgesic. Here, we tested the hypothesis t...

Descripció completa

Dades bibliogràfiques

Autors principals:	Luis G. Rivera-García, Adela M. Francis-Malavé, Zachary W. Castillo, Calvin D. Uong, Torri D. Wilson, P. A. Ferchmin, Vesna Eterovic, Michael D. Burton, Yarimar Carrasquillo
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2024-01-01
Col·lecció:	Journal of Inflammation
Matèries:	Inflammatory pain Tobacco cembranoid 4R Hyperalgesia Paw edema α7 nicotinic acetylcholine receptors
Accés en línia:	https://doi.org/10.1186/s12950-023-00373-8
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!