Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

<p>Abstract</p> <p>Background</p> <p>Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production of pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis is thought to play an important role in SMA, which is cha...

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Главные авторы:	Boeuf Philippe S, Loizon Séverine, Awandare Gordon A, Tetteh John KA, Addae Michael M, Adjei George O, Goka Bamenla, AL Kurtzhals Jørgen, Puijalon Odile, Hviid Lars, Akanmori Bartholomew D, Behr Charlotte
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2012-08-01
Серии:	Malaria Journal
Предметы:	Malaria Anaemia Cerebral malaria Severe malarial anaemia Monocytes T cells CD69 HLA-DR Monocyte de-activation, TNF IL-10 Cytokines
Online-ссылка:	http://www.malariajournal.com/content/11/1/253
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