Código QR (código de barras bidimensional)

Potent antitumor activity of a bispecific T-cell engager antibody targeting the intracellular antigen KRAS G12V

Kirsten Rat Sarcoma viral oncogene homolog (KRAS) is one of the most frequent oncogenes. However, there are limited treatment options due to its intracellular expression. To address this, we developed a novel bispecific T-cell engager (BiTE) antibody targeting HLA-A2/KRAS G12V complex and CD3 (HLA-...

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Principais autores: Changchang Lu, Lu Zou, Qiaoli Wang, Mengna Sun, Tianyu Shi, Shuang Xu, Fanyan Meng, Juan Du
Formato: Artigo
Idioma:Inglês
Publicado em: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2024-05-01
coleção:Biomolecules & Biomedicine
Assuntos:
Bispecific antibody
KRAS G12V
intracellular tumor antigen
cancer
Acesso em linha:https://www.bjbms.org/ojs/index.php/bjbms/article/view/10431
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