Site-Specific Protein Modifications by an Engineered Asparaginyl Endopeptidase from Viola canadensis

Asparaginyl endopeptidases (AEPs) or legumains are Asn/Asp (Asx)-specific proteases that break peptide bonds, but also function as peptide asparaginyl ligases (PALs) that make peptide bonds. This ligase activity can be used for site-specific protein modifications in biochemical and biotechnological...

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Autori principali:	Yu Chen, Dingpeng Zhang, Xiaohong Zhang, Zhen Wang, Chuan-Fa Liu, James P. Tam
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-10-01
Serie:	Frontiers in Chemistry
Soggetti:	asparaginyl endopeptidases peptide asparaginyl ligases ligase-activity determinant Viola canadensis cell surface labeling protein engineering
Accesso online:	https://www.frontiersin.org/articles/10.3389/fchem.2021.768854/full
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