Purification of Functional HEV-ORF2 Protein from Inclusion Bodies for Vaccine and Diagnostic Applications

Introduction: Hepatitis E virus (HEV) causes emerging diseases in poor regions of the world. The ORF2 is the only protein encoded by the virus to make the viral capsid. The aggregation of proteins into inclusion bodies (IBs) while expressing ORF2 is a major challenge in bioengineering. Methods: The...

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Principais autores:	Fatemeh Motevalli, Mohammad Reza Amiran, Mazyar Etemadzadeh, Golnaz Bahramali, Soroush Sardari, Seyede Zahra Moravej, Pooneh Rahimi, Abolfazl Fateh, Seyed Alireza Seyed Siamdoust, Mohammad Ali Zaheri Birgani, Mojtaba Hamidi-Fard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Pasteur Institute of Iran 2020-06-01
coleção:	Vaccine Research
Assuntos:	hepatitis e virus orf2 inclusion bodies protein solubilization
Acesso em linha:	http://vacres.pasteur.ac.ir/article-1-207-en.html
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