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Estrogen Receptor Binding of Xenoestrogens and Phytoestrogens in Japanese Quail (Coturnix japonica)

Estrogenic compounds must bind to estrogen receptors (ER) and modulate estrogen-sensitive gene expression. However, various in vivo and in vitro assays have established that xenoestrogens and phytoestrogens are rather weak estrogens, with a 5,000- to 10,000-fold lower binding affinity to ER than es...

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Main Authors: Ahmed M. Hanafy, Tomohiro Sasanami, Kouhei Ichikawa, Kiyoshi Shimada, Makoto Mori
Format: Artigo
Language:Inglês
Published: Japan Poultry Science Association 2004-01-01
Series:The Journal of Poultry Science
Subjects:
estrogen receptor
endocrine-disrupting chemicals
phytoestrogens
japanese quail
recombinant erα
Online Access:https://www.jstage.jst.go.jp/article/jpsa/41/1/41_1_30/_pdf/-char/en
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