Efferocytosis-associated genes serve as prognostic biomarkers for pancreatic ductal adenocarcinoma and identify P2RY6 as a therapeutic target

BackgroundPancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor with poor prognosis. Efferocytosis, an essential process for clearing apoptotic cells, is involved in shaping immunosuppressive microenvironment, facilitating tumor immune evasion. This study aims to evaluate the prognosti...

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Principais autores:	Xiangjun Wang, Wei Wang, Chuanxin Yang, Puxiongzhi Wang, Yangming Liu, Liqin Yu, Sijie Zhang, Xiaoyu Yan, Jian Wang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-11-01
סדרה:	Frontiers in Immunology
נושאים:	pancreatic ductal adenocarcinoma efferocytosis prognostic signature immunosuppressive microenvironment P2RY6 MRS-2578
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1708441/full
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