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Fabrication of biomimetic topological micropattern arrays to induce anisotropic/isotropic orientation of fibroblast

During fibroblast activation, fibroblasts exhibit remarkable heterogeneity characterized by distinct subtypes with unique molecular markers and specialized functions. In cancer and fibrosis, fibroblasts drive extracellular matrix (ECM) remodeling and actin stress fiber contractility, thereby inducin...

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Principais autores: Ping Yang, Xinglong Zhu, Yi Li, Hehan Feng, Yang Deng, Yanyan Zhou, Mumin Shao, Ji Bao
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-06-01
Serier:MethodsX
Fag:
Micropattern arrays
Extracellular matrix
Topology
Fibroblast
Anisotropy
Isotropy
Online adgang:http://www.sciencedirect.com/science/article/pii/S221501612600049X
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