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Trafficking and effect of released DNA on cGAS-STING signaling pathway and cardiovascular disease

Evidence from clinical research and animal studies indicates that inflammation is an important factor in the occurrence and development of cardiovascular disease (CVD). Emerging evidence shows that nucleic acids serve as crucial pathogen-associated molecular patterns (PAMPs) or non-infectious damage...

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Sparad:
Huvudupphov: Zimo Zhou, Changhan Ou-yang, Qingjie Chen, Zhanhong Ren, Xiying Guo, Min Lei, Chao Liu, Xiaosong Yang
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2023-12-01
Serie:Frontiers in Immunology
Ämnen:
dsDNA
cGAS-STING
innate immune system
inflammation
cardiovascular disease
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287130/full
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