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Target-small decoy search strategy for false discovery rate estimation

Abstract Background One of the most important steps in peptide identification is to estimate the false discovery rate (FDR). The most commonly used method for estimating FDR is the target-decoy search strategy (TDS). While this method is simple and effective, it is time/space-inefficient because it...

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Hauptverfasser: Hyunwoo Kim, Sangjeong Lee, Heejin Park
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-08-01
Schriftenreihe:BMC Bioinformatics
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Online-Zugang:http://link.springer.com/article/10.1186/s12859-019-3034-8
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