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Multiple functional variants in the IL1RL1 region are pretransplant markers for risk of GVHD and infection deaths

Abstract: Graft-versus-host disease (GVHD) and infections are the 2 main causes of death without relapse after allogeneic hematopoietic cell transplantation (HCT). Elevated soluble serum simulation-2 (sST2), the product of IL1RL1 in plasma/serum post-HCT, is a validated GVHD biomarker. Hundreds of S...

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Detalhes bibliográficos
Principais autores: Ezgi Karaesmen, Theresa Hahn, Alexander James Dile, Abbas A. Rizvi, Junke Wang, Tao Wang, Michael D. Haagenson, Leah Preus, Qianqian Zhu, Qian Liu, Li Yan, Song Liu, Christopher A. Haiman, Daniel Stram, Loreall Pooler, Xin Sheng, David Van Den Berg, Guy Brock, Amy Webb, Philip L. McCarthy, Marcelo C. Pasquini, Stephen R. Spellman, Stephanie J. Lee, Sophie Paczesny, Lara E. Sucheston-Campbell
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019-08-01
coleção:Blood Advances
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2473952920300331
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