Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes

Over 18 million disease cases and half a million deaths worldwide are estimated to be caused annually by Group A Streptococcus. A vaccine to prevent GAS disease is urgently needed. SpyCEP (Streptococcus pyogenes Cell-Envelope Proteinase) is a surface-exposed serine protease that inactivates chemokin...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sophie McKenna, Enrico Malito, Sarah L. Rouse, Francesca Abate, Giuliano Bensi, Emiliano Chiarot, Francesca Micoli, Francesca Mancini, Danilo Gomes Moriel, Guido Grandi, Danuta Mossakowska, Max Pearson, Yingqi Xu, James Pease, Shiranee Sriskandan, Immaculada Margarit, Matthew J. Bottomley, Stephen Matthews
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Association for the Advancement of Science (AAAS) 2020-01-01
Цуврал:	Computational and Structural Biotechnology Journal
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2001037020300076
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!