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Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8+ T Cell Receptors

T cells provide essential immunosurveillance to combat and eliminate infection from pathogens, yet these cells can also induce unwanted immune responses via T cell receptor (TCR) cross-reactivity, also known as heterologous immunity. Indeed, pathogen-induced TCR cross-reactivity has shown to be a co...

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Detalhes bibliográficos
Principais autores: Louise C. Rowntree, Heleen van den Heuvel, Jessica Sun, Lloyd J. D'Orsogna, Thi H. O. Nguyen, Frans H. J. Claas, Jamie Rossjohn, Tom C. Kotsimbos, Anthony W. Purcell, Nicole A. Mifsud
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-02-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.00248/full
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