Axonal degeneration in the anterior insular cortex is associated with Alzheimer’s co-pathology in Parkinson’s disease and dementia with Lewy bodies

Abstract Background Axons, crucial for impulse transmission and cellular trafficking, are thought to be primary targets of neurodegeneration in Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Axonal degeneration occurs early, preceeding and exceeding neuronal loss, and contributes to t...

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Bibliografiske detaljer

Principais autores:	Yasmine Y. Fathy, Laura E. Jonkman, John J. Bol, Evelien Timmermans, Allert J. Jonker, Annemieke J. M. Rozemuller, Wilma D. J. van de Berg
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2022-12-01
Serier:	Translational Neurodegeneration
Fag:	α-Synuclein Insular subregions Axonal length density Alzheimer’s disease pathology Neurofilament Myelin
Online adgang:	https://doi.org/10.1186/s40035-022-00325-x
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