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The Relationship of the Mechanisms of the Pathogenesis of Multiple Sclerosis and the Expression of Endogenous Retroviruses

Two human endogenous retroviruses of the HERV-W family can act as cofactors triggering multiple sclerosis (MS): MS-associated retrovirus (MSRV) and ERVWE1. Endogenous retroviral elements are believed to have integrated in our ancestors’ DNA millions of years ago. Their involvement in the pathogenesi...

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Principais autores: Vera R. Lezhnyova, Ekaterina V. Martynova, Timur I. Khaiboullin, Richard A. Urbanowicz, Svetlana F. Khaiboullina, Albert A. Rizvanov
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-12-01
Serier:Biology
Fag:
HERV-W
ERVWE1
MSRV
multiple sclerosis
citrullination
CpG methylation
Online adgang:https://www.mdpi.com/2079-7737/9/12/464
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