Structural basis for functional tetramerization of lentiviral integrase.
Experimental evidence suggests that a tetramer of integrase (IN) is the protagonist of the concerted strand transfer reaction, whereby both ends of retroviral DNA are inserted into a host cell chromosome. Herein we present two crystal structures containing the N-terminal and the catalytic core domai...
Na minha lista:
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2009-07-01
|
| coleção: | PLoS Pathogens |
| Acesso em linha: | http://europepmc.org/articles/PMC2705190?pdf=render |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|